1- Comparison_Results folder This folder contains two folders, Excel_Files and Logs_and_PDBs. 1.1 Excel_Files This folder contains all the excel files that contain the results. These files were used to generate the comparison tables. Each excel has many columns, such as R-free, R-work and many others. These are the columns we used in this Comparison; File: PDB code with its resolution and extra information Resolution: density map resolution TimeTaking : execution time R-factor (0 Cycle) : R-work calculated from REFMAC zero cycle R-free (0 Cycle): R-free calculated from REFMAC zero cycle F-mapCorrelation : initial map quality BuiltPDB : set to T when a pipeline built at least a one protein structure even if this structure is not a final structure. Intermediate: set to T when a protein structure is not a final model. Completeness: the percentage of its residues whose C alpha atoms have the same residue type as, and coordinates within 1 Å of, those of the corresponding processed deposited model from the Protein Data Bank (PDB). SHELXE completeness was calculated from only C alpha in correct positions within 1.0 Å because SHELXE only builds the main chain. 1.2 Logs_and_PDBs contains logs and PDBs for all the pipelines with its intermediate logs and PDBs 2- Datasets folder contains the mtz, sequence files and deposited PDB 3- Experiment folder contains the required scripts and files to produce the comparison results. Also, a README file that explains all steps to produce the comparison results.